Beta-Caryophyllene Terpene


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Beta-Caryophyllene is a distinctively spicy-sweet terpene with a woody, clove-like aroma. Beta-Caryophyllene is commonly found in black pepper, cinnamon, cloves, hops, basil, oregano, and cannabis.

  • Pain Relief
  • Anxiety Relief
  • Mood Booster
  • Immunity Support
  • Anti-inflammatory

Terpenes are completely natural, but they are highly potent and should be used with care. Once diluted properly, terpene isolates are safe to apply and ingest.

See our dilution instructions below.


Beta-Caryophyllene has a broad range of benefits that include relieving pain, depression, and anxiety. This is due to its unique property as the only known phytocannabinoid outside of the cannabis genus. Photo-cannabinoids (produced by plants) emulate the behavior of endo-cannabinoids (produced by the body). These neurotransmitters help regulate essential body systems like appetite, sleep, pain, pleasure, mood, and inflammation.

Think of terpenes as even purer forms of essential oils. They are the chemical compounds that are responsible for a plant’s aroma, flavor, and physiological effects. Terpenes are present in cannabis, as well as many other plants, herbs, and fruits.

Beta-Caryophyllene Qualities & Benefits

Aroma & Taste: Beta-Caryophyllene is a distinctively spicy-sweet terpene with a woody, clove-like aroma. Beta-Caryophyllene is commonly found in black pepper, cinnamon, cloves, hops, basil, oregano, and cannabis.

Pain Relief: As a phytocannabinoid, beta-Caryophyllene interacts with the body’s CB2 receptors in the endocannabinoid system (ECS). This property activates its benefits as an analgesic (pain reliever). Specifically, a 2014 German study found that the beta-Caryophyllene terpene helped relieve pain associated with inflammation, such as arthritis.

Anxiety Relief & Mood Booster: Similarly, beta-Caryophyllene’s interaction with CB2 receptors can also relieve stress and anxiety. Scientists have determined that CB2 receptors influence the release of dopamine, the “feel-good” chemical. Additionally, this terpene was found to protect anandamide, a neurotransmitter known as the “bliss molecule.”

Immunity Support: By binding to CB2 receptors, the beta-Caryophyllene terpene helps support the immune system. In 2013, researchers determined that CB2 receptors were linked to immune function. Furthermore, researchers have discovered that individuals with low cannabinoid levels are more vulnerable to disease.

Anti-inflammation: Several studies have found that beta-Caryophyllene can relieve inflammation. Though inflammation is typically a protective mechanism, too much can result in additional health consequences. As a phytocannbinoid, beta-Caryophyllene helps balance inflammation responses to injury, as well as reduce swelling and scarring. Additionally, because of its analgesic properties, the beta-Caryophyllene terpene can provide targeted injury relief.

Cannabis Cultivars: Cultivars known for their beta-Caryophyllene profiles are Sour Diesel, Girl Scout Cookies, Bubbah Kush, and Chem Dog.

How to use our Terpenes:

Terpenes can be enjoyed aromatically, topically, or ingested in foods and drinks. Many people love adding them to diffusers, serums, lotions, even cocktails.

Terpenes are not psychoactive and do not contain cannabinoids, but they are still very powerful. They should always be diluted and are not intended to be used at full potency. Similar to essential oils, terpenes do not mix with water, but they can be diluted with carrier oils and alcohol.

How to dilute our Terpenes:

As a general rule of thumb, we recommend using no more than a 1% concentration by volume. This equates to about 1-2 drops per 8 oz.

  • Carrier Oils: Add 1-2 drops per 8 oz. of volume and mix well. For topical or aromatic use, further additions should be added and tested in 1-2 drop increments. We recommend using MCTs, virgin coconut oil, hemp oil, extra virgin olive oil, or avocado oil.
  • Alcohol/Spirits: Add 1 drop per glass. Add to glass and swirl, or use as a bitters.
  • Wine/Beer/Cider: Add 1 drop per glass. Add to glass and swirl.
  • Soda Water: Add 1 drop per glass. Though terpenes do not mix with water, we’ve found that carbonation enhances the aroma and taste of the terpene.

To obtain more consistent results, measure precisely with instruments like pipettes, graduated cylinders, and burets.

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